A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma (NCT06748053)
A Multicentre, Randomized, Double-Blind, Placebo Controlled, Dose Finding, Parallel Group, Phase 2 Study of an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma
🩺 Plain-English Summary (8th-Grade Level)
This study is trying to find the right dose of a long-lasting medicine called GSK5784283 for people with asthma that remains uncontrolled even though they are using regular asthma treatments. GSK5784283 blocks the action of an inflammatory protein called TSLP that may be contributing to your asthma. The study will be conducted in two parts - Part A (dose finding phase) and Part B (extended dosing phase). Part A will assess the lung function, asthma control, participant safety and certain markers of asthma inflammation in the air you breath out and in your blood. Part B will assess the safety and long-term effects of the repeated or single doses of GSK5784283.
Who can join: Review the eligibility criteria below.
Location: GSK Investigational Site — Little Rock, Arkansas
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (134 Sites)
Showing the first 25 of 134 sites.
- GSK Investigational Site — Little Rock, Arkansas
- GSK Investigational Site — Long Beach, California
- GSK Investigational Site — Los Angeles, California
- GSK Investigational Site — Redding, California
- GSK Investigational Site — Riverside, California
- GSK Investigational Site — Sacramento, California
- GSK Investigational Site — San Jose, California
- GSK Investigational Site — Colorado Springs, Colorado
- GSK Investigational Site — Lakewood, Colorado
- GSK Investigational Site — Wheat Ridge, Colorado
- GSK Investigational Site — New Haven, Connecticut
- GSK Investigational Site — Aventura, Florida
- GSK Investigational Site — Hialeah, Florida
- GSK Investigational Site — Lake Worth, Florida
- GSK Investigational Site — Leesburg, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Miami, Florida
- GSK Investigational Site — Plantation, Florida
- GSK Investigational Site — Tampa, Florida
- GSK Investigational Site — Skokie, Illinois
- GSK Investigational Site — Shreveport, Louisiana
- GSK Investigational Site — Lathrup Village, Michigan
- GSK Investigational Site — Warren, Michigan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma — Saraland, Alabama
- Reduce IDentified UNcontrolled Asthma — San Diego, California
- REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study — La Jolla, California
Explore by condition: All Asthma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.