๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-13

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa) (NCT06749457)

A Phase I/IIa Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Pharmacokinetics of AZD7760 in Healthy Participants and in Patients With End-stage Kidney Disease Receiving Hemodialysis Through a Central Venous Catheter

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis through a central venous catheter (Phase IIa).

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Huntsville, Alabama

Age range: 18 Years to 55 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (44 Sites)

Showing the first 25 of 44 sites.

  • Research Site โ€” Huntsville, Alabama
  • Research Site โ€” Chula Vista, California
  • Research Site โ€” Chula Vista, California
  • Research Site โ€” Glendale, California
  • Research Site โ€” Granada Hills, California
  • Research Site โ€” Los Angeles, California
  • Research Site โ€” Northridge, California
  • Research Site โ€” Northridge, California
  • Research Site โ€” Oxnard, California
  • Research Site โ€” Riverside, California
  • Research Site โ€” San Dimas, California
  • Research Site โ€” Tarzana, California
  • Research Site โ€” Valencia, California
  • Research Site โ€” Victorville, California
  • Research Site โ€” Englewood, Colorado
  • Research Site โ€” Bradenton, Florida
  • Research Site โ€” Coral Springs, Florida
  • Research Site โ€” Hollywood, Florida
  • Research Site โ€” Orlando, Florida
  • Research Site โ€” Tampa, Florida
  • Research Site โ€” Lawrenceville, Georgia
  • Research Site โ€” Chicago, Illinois
  • Research Site โ€” Chicago, Illinois
  • Research Site โ€” Iowa City, Iowa
  • Research Site โ€” Lexington, Kentucky

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—