๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-22

SLV-154 Treatment of Advanced Cancers (NCT06771219)

A Phase 1 Dose-Escalation/Expansion Study of SLV-154 in Subjects With Advanced Cancers

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Solve Therapeutics

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase 1 study comprising a Phase 1a dose-escalation portion and a Phase 1b expansion portion evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-154 across a range of dose levels when administered to subjects with advanced solid tumors.

Who can join: Review the eligibility criteria below.

Location: Hoag Memorial Hospital Presbyterian โ€” Newport Beach, California

Age range: 12 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (10 Sites)

  • Hoag Memorial Hospital Presbyterian โ€” Newport Beach, California
  • Washington University โ€” St Louis, Missouri
  • Astera Cancer Care โ€” East Brunswick, New Jersey
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • University Hospitals Cleveland Medical Center โ€” Cleveland, Ohio
  • MD Anderson Cancer Center โ€” Houston, Texas
  • Oncology Consultants โ€” Houston, Texas
  • Mays Cancer Center; University of Texas Health San Antonio โ€” San Antonio, Texas
  • University of Washington / Fred Hutchinson Cancer Center โ€” Seattle, Washington
  • Northwest Medical Specialties, PLLC โ€” Tacoma, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (425) 894-2558

Email: hren@solvetx.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Advanced Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—