๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-13

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS) (NCT06773910)

An Open-label, Randomized Study of BMS-986489 (Atigotatug + Nivolumab Fixed-dose Combination) vs Durvalumab as Consolidation Therapy Following Chemoradiotherapy in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: SCRI Development Innovations, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is an open-label, randomized study of BMS-986489 (atigotatug + nivolumab fixed-dose combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants. The main goals of this study are to: * Evaluate the efficacy of BMS-986489 vs durvalumab * Evaluate the safety profile of BMS-986489

Who can join: Review the eligibility criteria below.

Location: Southern Cancer Center โ€” Daphne, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (34 Sites)

Showing the first 25 of 34 sites.

  • Southern Cancer Center โ€” Daphne, Alabama
  • Sansum Clinic โ€” Santa Barbara, California
  • Florida Cancer Specialists - South โ€” Fort Myers, Florida
  • University of Miami - Sylvester Cancer Center โ€” Miami, Florida
  • Ocala Oncology Center โ€” Ocala, Florida
  • Florida Cancer Specialists - North โ€” Orange City, Florida
  • Cancer Care Centers of Brevard โ€” Palm Bay, Florida
  • Florida Cancer Specialists - East โ€” West Palm Beach, Florida
  • Piedmont Healthcare - Atlanta โ€” Atlanta, Georgia
  • Illinois Cancer Specialists โ€” Arlington Heights, Illinois
  • Illinois Cancer Care โ€” Peoria, Illinois
  • Indiana University Simon Cancer Center โ€” Indianapolis, Indiana
  • Baptist Health - Corbin โ€” Corbin, Kentucky
  • Baptist Health - Lexington โ€” Lexington, Kentucky
  • Baptist Health - Louisville โ€” Louisville, Kentucky
  • Minnesota Oncology Hematology โ€” Maple Grove, Minnesota
  • Missouri Cancer Associates โ€” Columbia, Missouri
  • White Plains Hospital Physician Associates โ€” White Plains, New York
  • Carolina Cancer Research Center โ€” Wilson, North Carolina
  • Oncology Hematology Care โ€” Cincinnati, Ohio
  • The Ohio State University - Arthur James Cancer Hospital & Solove Research Institute โ€” Columbus, Ohio
  • Mid Ohio Hem/ Onc dba The Mark H Zangmeister Center โ€” Columbus, Ohio
  • Oncology Associates of Oregon (Willamette Valley Cancer Institute and Research Center) โ€” Eugene, Oregon
  • Tennessee Cancer Specialists โ€” Knoxville, Tennessee
  • SCRI Oncology Partners โ€” Nashville, Tennessee

๐Ÿ“ž Contact the Study Coordinator

Phone: (844) 710-6157

Email: SCRI.InnovationsMedical@scri.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—