🏛️ Verified NIH Record • Updated 2026-05-04
Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea (NCT06776432)
A Phase 2A Double-Blind Randomized, Controlled, Dose Escalation, Parallel- Arm, Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Shionogi
🩺 Plain-English Summary (8th-Grade Level)
The primary purpose of this study is to evaluate the effectiveness of sivopixant, acetazolamide and SASS-001 in adults with sleep apnea with a central component.
Who can join: Review the eligibility criteria below.
Location: Altman Clinical and Translational Research Institute (ACTRI) — La Jolla, California
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Altman Clinical and Translational Research Institute (ACTRI) — La Jolla, California
- Teradan Clinical Trials — Brandon, Florida
- PharmaDev Clinical Research Institute, LLC — Miami, Florida
- Infinity Medical Research — North Dartmouth, Massachusetts
- John D. Dingell VA Medical Center — Detroit, Michigan
- Mayo Clinic — Rochester, Minnesota
- Intrepid Research, LLC — Cincinnati, Ohio
- OnSite Clinical Solutions — Rock Hill, South Carolina
- Huntsville Research Institute LLC — Huntsville, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Sleep Apnea
- Mechanisms of Prediabetic States in Sleep Apnea — Chicago, Illinois
- Technology-Supported Treatment of Sleep Apnea in Prediabetes — Chicago, Illinois
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers — West Los Angeles, California
- Janus II Feasibility — Scottsdale, Arizona
- Sleep Disordered Breathing With Opioid Use — Detroit, Michigan
Explore by condition: All Sleep Apnea clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.