Safety, Tolerability and PK of ATTO-1310 in Healthy Volunteers and Patients With Atopic Dermatitis and Patients With Chronic Pruritus (NCT06787586)
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multi-Part, Single Ascending Dose and Multiple Ascending Dose Study to Assess the Safety, Tolerability, and PK of ATTO1310 in Adult Volunteers, Patients With Atopic Dermatitis, and Patients With Chronic Pruritus
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to assess the safety, tolerability, and pharmacokinetics of ATTO-1310 in healthy adults, patients with atopic dermatitis and patients with chronic pruritus. The main questions it aims to answer are: What medical problems do participants have when taking ATTO-1310? How long does ATTO-1310 stay in the body after dosing? Researchers will compare ATTO-1310 to a placebo (a look-alike substance that contains no drug). Participants will be dosed with ATTO-1310 or a placebo, visit the clinic for checkups and tests, and keep a diary of their symptoms.
Who can join: Review the eligibility criteria below.
Location: Attovia Clinical Site 103 — Encinitas, California
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (17 Sites)
- Attovia Clinical Site 103 — Encinitas, California
- Attovia Clinical Site 116 — Rocklin, California
- Attovia Clinical Site 107 — Sacramento, California
- Attovia Clinical Site 109 — Coral Gables, Florida
- Attovia Clinical Site 118 — Margate, Florida
- Attovia Clinical Site 102 — Plainfield, Indiana
- Attovia Clinical Site 104 — Saint Joseph, Missouri
- Attovia Clinical Site 106 — Reno, Nevada
- Attovia Clinical Site 114 — New York, New York
- Attovia Clinical Site 119 — New York, New York
- Attovia Clinical Site 108 — San Antonio, Texas
- Attovia Clinical Site 110 — Fredericton, New Brunswick
- Attovia Clinical Site 111 — Newmarket, Ontario
- Attovia Clinical Site 112 — Peterborough, Ontario
- Attovia Clinical Site 113 — Toronto, Ontario
- Attovia Clinical Site 105 — Montreal, Quebec
- Altasciences — Montreal, Quebec
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.