A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy (NCT06797869)
Efficacy and Safety of co Administered Cagrilintide and Semaglutide (CagriSema) Once Weekly Versus Placebo in Participants With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy
🩺 Plain-English Summary (8th-Grade Level)
This study will look at the effects of CagriSema in people with both type 2 diabetes and painful diabetic peripheral neuropathy, compared to placebo. Participants will either get an active medicine or a "dummy" medicine (placebo). Which treatment participants get is decided by chance. In this study the active, investigational medicine is called CagriSema. Doctors cannot yet prescribe CagriSema. For each participant, the study will last for about 10 months.
Who can join: Review the eligibility criteria below.
Location: eStudySite — La Mesa, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (54 Sites)
Showing the first 25 of 54 sites.
- eStudySite — La Mesa, California
- Linda Vista Health Care Ctr — San Diego, California
- My Preferred Research — Miami, Florida
- New Horizon Research Center — Miami, Florida
- Renstar Medical Research — Ocala, Florida
- Foot & Ankle Center of Illinois — Springfield, Illinois
- Velocity Clinical Research Rockville — Rockville, Maryland
- Amicis Centers of Clinical Research — St Louis, Missouri
- DM Clinical - CyFair — Albuquerque, New Mexico
- Southgate Medical Group, LLP — West Seneca, New York
- Piedmont Healthcare/Research — Statesville, North Carolina
- Lillestol Research LLC — Fargo, North Dakota
- Oregon Health & Science University — Portland, Oregon
- Clinical Res Collaborative — Cumberland, Rhode Island
- DM Clinical - CyFair — Houston, Texas
- Radiance Clinical Research — Lampasas, Texas
- DM Clinical - CyFair — San Antonio, Texas
- DM Clinical Research — San Antonio, Texas
- Velocity Clinical Research Portsmouth — Suffolk, Virginia
- G.A. Research Associates Ltd. — Moncton, New Brunswick
- Centricity Research Brampton — Brampton, Ontario
- Centricity Clinical Research Burlington — Burlington, Ontario
- Centricity Research Etobicoke — Etobicoke, Ontario
- Premier Clinical Trial Research Network (PCTRN) — Hamilton, Ontario
- Diabetes Heart Research Centre — Toronto, Ontario
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Diabetes Mellitus, Type 2
- Integrating Abbott Point-of-Care Technologies and the Community Scientist Model to Support HbA1c Testing Per ADA — Santa Barbara, California
- Diabetes Discharge Transitional CGM Study (DDT-CGM) — Logan, Utah
- Food Delivery, Remote Monitoring, and Coaching-Enhanced Education for Optimized Diabetes Management (FREEDOM) — Birmingham, Alabama
- MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia — Las Vegas, Nevada
- Strategies to Improve Well-Being and Diabetes Management — Westbrook, Maine
- Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes — Montreal, Quebec
Explore by condition: All Diabetes Mellitus, Type 2 clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.