Focused Ultrasound for PTSD in Veterans (NCT06820138)
Low Intensity Focused Ultrasound for Posttraumatic Stress Disorder
🩺 Plain-English Summary (8th-Grade Level)
The goal of this study is to develop a new, non-invasive brain stimulation modality called low intensity focused ultrasound (FUS) as a psychiatric rehabilitation treatment for posttraumatic stress disorder (PTSD). FUS delivers energy comparable to that involved in diagnostic ultrasound but in a millimeter-sized envelope. Unlike currently available methods, the maximal FUS energy is delivered at a distance from a transducer on the scalp. Therefore, its promise is that it can deliver focal and reversible modulation to deeper brain regions involved in PTSD. The investigator team has previously conducted first-in-human research in FUS, and this study builds upon that work to conduct a phase II, dose-finding study. This study will pursue two Aims; the first is whether FUS to the amygdala can improve symptoms, and the second will evaluate whether FUS improves function by reduced disability, over a 1-month period. Short and longer-term effects of FUS will be measured and all FUS parameters are within FDA-defined safety thresholds for diagnostic ultrasound.
Who can join: Review the eligibility criteria below.
Location: Providence VA Medical Center, Providence, RI — Providence, Rhode Island
Age range: 22 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Providence VA Medical Center, Providence, RI — Providence, Rhode Island
📞 Contact the Study Coordinator
Phone: (401) 273-7100
Email: noah.philip@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Posttraumatic Stress Disorder
- Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests — Seattle, Washington
- A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD — Birmingham, Alabama
- Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes — Grand Rapids, Michigan
- Using Data Science To Center Patient Perspectives in Mechanism Discovery — Malden, Massachusetts
- Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD — Palo Alto, California
- Enhancing Week-long Psychological Treatment for PTSD With Ketamine — New Haven, Connecticut
Explore by condition: All Posttraumatic Stress Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.