๐๏ธ Verified NIH Record โข Updated 2026-08-11
Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial (NCT06826755)
๐ข Recruiting Observational / Diagnostic ๐ Clinical Research Protocol Sponsor: Mayo Clinic
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this research is to study the effects of 12 weeks of melatonin supplementation compared to placebo in women who are in the menopause transition (perimenopause) and have high blood pressure.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic in Rochester โ Rochester, Minnesota
Age range: 40 Years to 55 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Mayo Clinic in Rochester โ Rochester, Minnesota
๐ Contact the Study Coordinator
Phone: (507) 255-8897
Email: PerimenopauseStdy@mayo.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Perimenopause
- Impact of Estradiol on Endothelial Function in Peri-Menopausal Women โ Newark, Delaware
- Occupational Disruption and Role Strain During Perimenopause โ Troy, New York
- Evaluation of the Effects of Lifestyle Medicine and Mindfulness-based Group Medical Visits on Stress, Microbiome, and Quality of Life in Women Experiencing Perimenopause and Menopause โ Columbus, Ohio
- Shatavari Root Extract for Perimenopausal Symptoms โ San Francisco, California
- Amygdala Insula Retraining in the Management of Perimenopause Symptoms โ Decorah, Iowa
Explore by condition: All Perimenopause clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.