EVR and EPO for Liver Transplant Tolerance (NCT06832189)
Everolimus and Epoetin for Sustained Liver Transplant Tolerance (EVEREST)(ITN101ST)
🩺 Plain-English Summary (8th-Grade Level)
This is an open label, single-arm, multicenter phase 1b study of stable adult liver transplant recipients on a tacrolimus (TAC)-based immunosuppression (IS) regimen who will transition from TAC to Everolimus (EVR), receive five doses of EPO and concurrently initiate phased withdrawal from EVR. The primary objective is to test the safety of administering Everolimus (EVR) and epoetin alfa (EPO) to induce operational tolerance in stable adult liver transplant recipients
Who can join: Review the eligibility criteria below.
Location: University of California San Francisco School of Medicine — San Francisco, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- University of California San Francisco School of Medicine — San Francisco, California
- Northwestern University Feinberg School of Medicine — Chicago, Illinois
- University of Pennsylvania Medical Center — Philadelphia, Pennsylvania
📞 Contact the Study Coordinator
Phone: (415) 476-2574
Email: Joanne.kwan@ucsf.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue — Cleveland, Ohio
- Normothermic Machine Perfusion of Steatotic Livers for Expansion of Donor Organ Pool — Boston, Massachusetts
- US National OCS Liver Perfusion (OLP) Registry — Birmingham, Alabama
Explore by condition: All Liver Transplant clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.