๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-02

Efficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist (NCT06851858)

A Phase II Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This Phase II study is a randomized, parallel group, double blinded, placebo-controlled, multicenter to evaluate the efficacy, safety, and tolerability of AZD6234 in adults with overweight or obesity and type 2 diabetes on stable GLP-1 RA therapy.

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Birmingham, Alabama

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (18 Sites)

  • Research Site โ€” Birmingham, Alabama
  • Research Site โ€” Mobile, Alabama
  • Research Site โ€” Doral, Florida
  • Research Site โ€” Jacksonville, Florida
  • Research Site โ€” Miami, Florida
  • Research Site โ€” Miami, Florida
  • Research Site โ€” Winter Park, Florida
  • Research Site โ€” Canton, Georgia
  • Research Site โ€” Fayetteville, Georgia
  • Research Site โ€” Chicago, Illinois
  • Research Site โ€” Oak Brook, Illinois
  • Research Site โ€” Newton, Kansas
  • Research Site โ€” Lexington, Kentucky
  • Research Site โ€” Kansas City, Missouri
  • Research Site โ€” Las Vegas, Nevada
  • Research Site โ€” Norman, Oklahoma
  • Research Site โ€” Knoxville, Tennessee
  • Research Site โ€” San Antonio, Texas

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Endocrinology clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—