🏛️ Verified NIH Record • Updated 2025-10-03
Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis (NCT06857240)
🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: The Cleveland Clinic
🩺 Plain-English Summary (8th-Grade Level)
This study will assess the safety and efficacy of topical ruxolitinib for treating the refractory cutaneous manifestations in patients with dermatomyositis. The investigators' hypothesis is that topical ruxolitinib will be both safe and effective for such patients.
Who can join: Review the eligibility criteria below.
Location: Cleveland Clinic — Cleveland, Ohio
Age range: 18 Years to 89 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Cleveland Clinic — Cleveland, Ohio
📞 Contact the Study Coordinator
Phone: (216) 445-8776
Email: dermatologyresearch@ccf.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Dermatomyositis
- A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis — Oceanside, California
- A Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Dermatomyositis — Phoenix, Arizona
- Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis — Palo Alto, California
- Adult and Juvenile Myositis — Atlanta, Georgia
- Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) — Philadelphia, Pennsylvania
Explore by condition: All Dermatomyositis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.