Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar (NCT06857435)
Autologous Point-of-Care Adipose Therapy for Reconstruction and Regeneration of Traumatized Skin: Delayed Injury/Scar
🩺 Plain-English Summary (8th-Grade Level)
The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can autologous layered composite grafting demonstrate non-inferiority compared to full-thickness skin grafting for delayed reconstruction of post-burn or trauma scar contracture? Researchers will compare the single-stage autologous layered composite grafting method to traditional methods to see if it improves healing outcomes, minimizes scarring, and reduces infection risk. Participants will: * Receive fat grafting at time of scar revision. * Undergo simultaneous split-thickness skin grafting for full soft-tissue reconstruction.
Who can join: Review the eligibility criteria below.
Location: Mercy Hospital — Pittsburgh, Pennsylvania
Age range: 18 Years
🧪 Interventions in This Study
- Full Thickness Skin Graft (FTSG) (PROCEDURE)
- Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting). (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Mercy Hospital — Pittsburgh, Pennsylvania
- Presbyterian Hospital — Pittsburgh, Pennsylvania
📞 Contact the Study Coordinator
Phone: (412) 641-8676
Email: shirleye@upmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Burns
- Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns — Phoenix, Arizona
- Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection — Oklahoma City, Oklahoma
- The Effects of Metformin on Morbidity and Mortality in Elderly Patients — Hamilton, Ontario
- A Phase I, Single-blind, Randomized Study of the Safety and Efficacy of Cellularized Integra® Using Autologous Burn-derived Stem Cells — Hamilton, Ontario
- A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes — Winnipeg, Manitoba
- 4-Aminopyridine to Treat Skin Burns — Tucson, Arizona
Explore by condition: All Burns clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.