🏛️ Verified NIH Record • Updated 2026-08-13
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients (NCT06857955)
A Randomized, Double-blind, Placebo-controlled, Multicenter, 12 Months Treatment Duration, Dose Finding Study, to Evaluate Efficacy, Safety and Pharmacodynamics of QCZ484 in Mild to Moderate Hypertensive Patients
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy, safety and tolerability of QCZ484 or placebo, given subcutaneously, every 6 months, at different dose levels in patients with mild to moderate hypertension
Who can join: Review the eligibility criteria below.
Location: SEC Clinical Research LLC — Andalusia, Alabama
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (73 Sites)
Showing the first 25 of 73 sites.
- SEC Clinical Research LLC — Andalusia, Alabama
- Longwood Research — Huntsville, Alabama
- The Center for Clinical Trials — Saraland, Alabama
- Elite Clinical Studies — Phoenix, Arizona
- Synexus Clinical Research US Inc — Tucson, Arizona
- NICRs Research Center — Garden Grove, California
- Valiance Clinical Research — Huntington Park, California
- Downtown L A Research Center Inc — Los Angeles, California
- Clinical Trials Research Sacramento — Sacramento, California
- Encompass Clinical Research — Spring Valley, California
- Clinical Research of Brandon LLC — Brandon, Florida
- ALL Medical Research LLC — Cooper City, Florida
- National Research Institute — Hialeah, Florida
- Cen Exel RCA — Hollywood, Florida
- East Coast Institute for Research — Jacksonville, Florida
- Entrust Clinical Research — Miami, Florida
- Inpatient Research Clinical LLC — Miami Lakes, Florida
- Renstar Medical Research — Ocala, Florida
- American Research Centers of FL — Pembroke Pines, Florida
- Cen Exel FCR — Tampa, Florida
- Cardiology Partners Clinical Research Institute — Wellington, Florida
- Centricity Research — Columbus, Georgia
- Javara Research — Fayetteville, Georgia
- Velocity Clinical Research — Savannah, Georgia
- Solaris Clinical Research — Meridian, Idaho
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension — Birmingham, Alabama
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Explore by condition: All Hypertension clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.