🏛️ Verified NIH Record • Updated 2025-10-15
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (NCT06858839)
A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Amgen
🩺 Plain-English Summary (8th-Grade Level)
The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
Who can join: Review the eligibility criteria below.
Location: Pinnacle Research Group LLC — Anniston, Alabama
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (243 Sites)
Showing the first 25 of 243 sites.
- Pinnacle Research Group LLC — Anniston, Alabama
- Alliance For Multispecialty Research - Daphne — Daphne, Alabama
- Alliance for Multispecialty Research Mobile — Mobile, Alabama
- Avacare Foothills Research Center — Phoenix, Arizona
- Ark Clinical Research- Tustin — Fountain Valley, California
- Long Beach Clinical Trials Services Inc — Long Beach, California
- Ark Clinical Research- Long Beach — Long Beach, California
- Catalina Research Institute — Montclair, California
- Artemis Institute for Clinical Research — Riverside, California
- Artemis Institute for Clinical Research — San Diego, California
- Apex Clinical Research — San Diego, California
- Southern California Clinical Research — Santa Ana, California
- Diablo Clinical Research — Walnut Creek, California
- Yale School of Medicine — New Haven, Connecticut
- Chase Medical Research LLC — Waterbury, Connecticut
- Indago Research and Health Center — Hialeah, Florida
- Jacksonville Center for Clinical Research — Jacksonville, Florida
- Clinical Neuroscience Solutions - Jacksonville — Jacksonville, Florida
- South Florida Wellness and Clinical Research Institute — Margate, Florida
- Optimus U Corporation — Miami, Florida
- Research Institute of South Florida — Miami, Florida
- Renstar Medical Research — Ocala, Florida
- Clinical Neuroscience Solutions - Orlando — Orlando, Florida
- Combined Research Orlando Phase I IV — Orlando, Florida
- Florida Institute for Clinical Research — Orlando, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.