ποΈ Verified NIH Record β’ Updated 2026-08-06
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis (NCT06863961)
A Phase II, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of RO7790121 in Patients With Moderate to Severe Atopic Dermatitis
π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic Sponsor: Hoffmann-La Roche
π©Ί Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the efficacy and safety of Afimkibart (also known as RO7790121) in participants with moderate to severe atopic dermatitis (AD).
Who can join: Review the eligibility criteria below.
Location: The Center for Dermatology Clinical Research β Fremont, California
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (60 Sites)
Showing the first 25 of 60 sites.
- The Center for Dermatology Clinical Research β Fremont, California
- UCLA Division of Dermatology β Los Angeles, California
- Dermatology Research Associate β Los Angeles, California
- AMR Fort Myers β Fort Myers, Florida
- Olympian Clinical Research β Tampa, Florida
- Hamilton Research, LLC β Alpharetta, Georgia
- Dermatology Affiliates Research Institute, LLC β Atlanta, Georgia
- Dawes Fretzin Clinical Res LLC β Indianapolis, Indiana
- Southern Indiana Clinical Trials β New Albany, Indiana
- Revival Research Institute, LLC β Troy, Michigan
- Regents of the University of Minnesota β Minneapolis, Minnesota
- Care Access Research - Hoboken β Hoboken, New Jersey
- Forest Hill Dermatology Group β Kew Gardens, New York
- Weill Cornell Medicine β New York, New York
- Centricity Research Columbus Dermatology β Columbus, Ohio
- Central Sooner Research β Oklahoma City, Oklahoma
- Oregon Health & Science University β Portland, Oregon
- Best Skin Research LLC β Camp Hill, Pennsylvania
- Arlington Research Center β Arlington, Texas
- Modern Research Associates β Dallas, Texas
- Reveal Research Institute β Dallas, Texas
- Clinica Ibis β Salvador, Estado de Bahia
- Centro de Estudos em Terapias Inovadoras ? CETI β Curitiba, ParanΓ‘
- Hospital de Clnicas de Porto Alegre β Porto Alegre, Rio Grande do Sul
- Santa Casa de Misericordia de Porto Alegre β Porto Alegre, Rio Grande do Sul
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atopic Dermatitis
- A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden β Birmingham, Alabama
- ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis β Phoenix, Arizona
- A Study of Barzolvolimab in Patients With Atopic Dermatitis β Birmingham, Alabama
- Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis β Chicago, Illinois
- A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis β Birmingham, Alabama
- A Study Evaluating APG777 in Atopic Dermatitis β Fountain Valley, California
Explore by condition: All Atopic Dermatitis clinical trials
π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.