Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis (NCT06865105)
A Phase 2 Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects With Active Psoriatic Arthritis
🩺 Plain-English Summary (8th-Grade Level)
Psoriatic arthritis (PsA) is a type of arthritis that happens when the body's immune system attacks healthy cells and tissues causing joint pain, stiffness, and swelling. Symptoms can get worse and go away for periods of time. This study will evaluate the efficacy and safety of targeted therapies through a series of substudies, for the treatment of active psoriatic arthritis and to assess the changes in disease symptoms. The therapies being assessed in this sub-study are risankizumab and lutikizumab. Participants will be randomized in a 1:1:1 ratio to one of the three treatment arms: lutikizumab monotherapy, risankizumab monotherapy or a combination therapy of lutikizumab and risankizumab. Around 120 participants will be enrolled in the study at approximately 40 sites worldwide. There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
Who can join: Review the eligibility criteria below.
Location: Newport Huntington Medical Group /ID# 272764 — Huntington Beach, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (37 Sites)
Showing the first 25 of 37 sites.
- Newport Huntington Medical Group /ID# 272764 — Huntington Beach, California
- Highlands Advanced Rheumatology And Arthritis Center - Avon Park /ID# 273085 — Avon Park, Florida
- Clinical Research Of West Florida - Phase I Unit /ID# 273198 — Clearwater, Florida
- HMD Research LLC /ID# 273086 — Orlando, Florida
- West Broward Rheumatology Associates /ID# 272892 — Tamarac, Florida
- Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 273199 — Tampa, Florida
- Clinic Of Dr. Robert Hozman/Clinical Investigation Specialists, Inc /ID# 272879 — Skokie, Illinois
- Willow Rheumatology and Wellness, PLLC /ID# 277354 — Willowbrook, Illinois
- Klein And Associates /ID# 272829 — Hagerstown, Maryland
- Paramount Medical Research and Consulting /ID# 272757 — Middleburg Heights, Ohio
- Altoona Center For Clinical Research /ID# 272593 — Duncansville, Pennsylvania
- Private Practice - Dr. Ramesh C. Gupta I /ID# 272897 — Memphis, Tennessee
- Tekton Research - West Gate /ID# 272765 — Austin, Texas
- Accurate Clinical Research - Houston /ID# 272754 — Houston, Texas
- Tekton Research, LLC /ID# 272901 — San Antonio, Texas
- Dynamed Clinical Research - Tomball /ID# 272760 — Tomball, Texas
- Centre de Recherche Musculo-Squelettique /ID# 274397 — Trois-Rivières, Quebec
- Dr. Latha Naik Medical Professional Corporation /ID# 272803 — Saskatoon, Saskatchewan
- Revmatologie /ID# 272367 — Brno, Brno-mesto
- L.K.N. Arthrocentrum /ID# 272366 — Hlučín, Moravian-Silesian Region
- Medical Plus s.r.o. /ID# 272363 — Uherské Hradiště,
- PV Medical Services s.r.o. /ID# 272368 — Zlín,
- Centre Hospitalier Universitaire de Nice - Hopital Pasteur /ID# 272771 — Nice, Alpes-Maritimes
- Infirmerie Protestante De Lyon /ID# 273731 — Caluire-et-Cuire, Auvergne-Rhône-Alpes
- Centre Hospitalier Régional Universitaire De Tours - Hôpital Trousseau /ID# 272762 — Chambray-lès-Tours, Indre-et-Loire
📞 Contact the Study Coordinator
Phone: (844) 663-3742
Email: abbvieclinicaltrials@abbvie.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Psoriatic Arthritis
- A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs — Gilbert, Arizona
- Psoriatic Arthritis D2P Screening — Philadelphia, Pennsylvania
- Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis — Dothan, Alabama
- Apremilast Pregnancy Exposure Registry — La Jolla, California
- Psorcast Mobile Study — Seattle, Washington
- A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy — Anniston, Alabama
Explore by condition: All Psoriatic Arthritis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.