🏛️ Verified NIH Record • Updated 2026-08-07

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment (NCT06883240)

A Multicenter Non-Interventional Study Evaluating Bleeds and Health-Related Quality Of Life in Patients With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Hoffmann-La Roche

🩺 Plain-English Summary (8th-Grade Level)

This non-interventional study (NIS) is designed to collect information on the effectiveness and safety of treatment received in routine clinical care, as well as measure the health-related quality of life (HRQoL) of participants with Type 3 von Willebrand disease (VWD) receiving prophylactic therapy per local standard of care (SOC) over an observation period of at least 24 weeks.

Who can join: Review the eligibility criteria below.

Location: UC Davis — Sacramento, California

Age range: 2 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (26 Sites)

Showing the first 25 of 26 sites.

  • UC Davis — Sacramento, California
  • University of Minnesota Medical Center — Minneapolis, Minnesota
  • Washington University School of Medicine — St Louis, Missouri
  • UZ Leuven Gasthuisberg — Leuven,
  • The Hospital for Sick Children — Toronto, Ontario
  • McGill University Health Center — Montreal, Quebec
  • IPS SURA Industriales Medellín — Medellín,
  • Hopital Claude Huriez - CHU Lille — Lille,
  • Groupe Hospitalier Necker Enfants Malades — Paris,
  • Universitätsklinikum Bonn — Bonn,
  • Gerinnungszentrum Rhein-Ruhr;Gerinnungsambulanz — Duisburg,
  • Hämophiliezentrum Med. Klinik III/Institut für Transfusionsmedizin — Frankfurt/M.,
  • Universita' Degli Studi La Sapienza-Ist.Di Ematologia — Rome, Lazio
  • IRCCS Ca' Granda Ospedale Maggiore Policlinico — Milan, Lombardy
  • AOU Careggi — Florence, Tuscany
  • Kurume University Hospital — Fukuoka,
  • Tokyo Medical University Hospital — Tokyo,
  • Erasmus MC — Rotterdam,
  • Instytut Hematologii i Transfuzjologii — Warsaw,
  • Charlotte Maxeke Johannesburg Academic Hospital — Johannesburg,
  • Hospital Universitario la Paz — Madrid,
  • Hospital Universtiario Virgen del Rocio — Seville,
  • Sahlgrenska Universitetssjukhuset — Gothenburg,
  • St Thomas' Hospital — London,
  • Great Ormond Street Hospital — London,

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗