Tirzepatide in PWS, HO and GNSO (NCT06901245)
The Effects of Tirzepatide in Young Adults With Prader-Willi Syndrome, Hypothalamic Obesity and General Non-Syndromic Obesity
🩺 Plain-English Summary (8th-Grade Level)
This research study is comparing the effectiveness of a weight loss medication called Tirzepatide in young adults with Prader-Willi Syndrome and/or hypothalamic obesity, as compared to young adults with obesity that is unrelated to a genetic syndrome or underlying medical cause. These groups will be given medication for 1 year to see how weight and other health factors are effected by the medication.
Who can join: Review the eligibility criteria below.
Location: Children's Minnesota — Saint Paul, Minnesota
Age range: 18 Years to 26 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Children's Minnesota — Saint Paul, Minnesota
- Vanderbilt University Medical Center — Nashville, Tennessee
- Seattle Children's Hospital — Seattle, Washington
📞 Contact the Study Coordinator
Phone: (651) 220-5730
Email: endocrineresearch@childrensmn.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Prader-Willi Syndrome
- A Study of Setmelanotide in Patients With Prader-Willi Syndrome — Gainesville, Florida
- A Clinical Evaluation of Non-Invasive Vagus Nerve Stimulation for Temper Outbursts in People With PWS — Palo Alto, California
- Open-Label Extension Study of DCCR in Patients With Prader-Willi Syndrome — Orange, California
- A Study of Pitolisant in Patients With Prader-Willi Syndrome — Los Angeles, California
- Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation — Kansas City, Missouri
Explore by condition: All Prader-Willi Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.