A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (NCT06907290)
A Global, Randomized, Open-label, Multicenter, Phase 2b/3 Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase 2b/3 study designed to evaluate the safety and efficacy of chronic treatment with brelovitug (a.k.a BJT-778; BTG) for chronic hepatitis delta virus (HDV) infection. The comparator in this study will be 24-weeks of delayed treatment. During the 24-weeks of delayed treatment, participants will complete the same visits and assessments as those randomized to initiate brelovitug immediately. At the completion of 24-week delayed treatment period, all participants will start treatment with brelovitug.
Who can join: Review the eligibility criteria below.
Location: 247 Garden Grove — Garden Grove, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (38 Sites)
Showing the first 25 of 38 sites.
- 247 Garden Grove — Garden Grove, California
- 242 Huntington Beach — Huntington Beach, California
- 252 Long Beach — Long Beach, California
- 244 Los Angeles — Los Angeles, California
- 250 Miami — Miami, Florida
- 251, Illinois — Chicago, Illinois
- 248 Lowa — Cities in Iowa, Iowa
- 254 Baltimore — Baltimore, Maryland
- 241, Massachusetts — Boston, Massachusetts
- 245 New York — New York, New York
- 256 New York — New York, New York
- 253 New York — New York, New York
- 255 New York — New York, New York
- 257 Philadelphia — Philadelphia, Pennsylvania
- 249 San Antonio — San Antonio, Texas
- 102 Melbourne — Melbourne, Victoria
- 101 Camperdown — Camperdown,
- 104 Liverpool — Liverpool,
- 703 Sliven — Sliven, Silven
- 705 Plovdiv — Plovdiv,
- 702 Bulgaria — Sofia,
- 706 Sofia — Sofia,
- 704 Stara Zagora — Stara Zagora,
- 233 Calgary — Calgary, Calgary
- 234 Alberta — Edmonton, Edmonton
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.