🏛️ Verified NIH Record • Updated 2026-05-11
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight (NCT06914895)
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Evaluating the Efficacy and Safety of Tirzepatide Once Weekly Compared to Placebo in Adult Participants With Type 1 Diabetes and Obesity or Overweight
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Eli Lilly and Company
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to find out how well and how safely tirzepatide works in adults who have type 1 diabetes and obesity or overweight. Participation in the study will last about 49 weeks.
Who can join: Review the eligibility criteria below.
Location: Sansum Diabetes Research Institute — Santa Barbara, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (146 Sites)
Showing the first 25 of 146 sites.
- Sansum Diabetes Research Institute — Santa Barbara, California
- Care Access - Santa Clarita — Santa Clarita, California
- University of Colorado Anschutz Medical Campus — Aurora, Colorado
- Atlanta Diabetes Associates — Atlanta, Georgia
- Orita Clinical Research — Decatur, Georgia
- North Georgia Clinical Research — Woodstock, Georgia
- East-West Medical Research Institute — Honolulu, Hawaii
- Rocky Mountain Clinical Research — Idaho Falls, Idaho
- Southern Illinois University School of Medicine — Springfield, Illinois
- Indiana University Health University Hospital — Indianapolis, Indiana
- Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa
- Endocrine and Metabolic Consultants — Rockville, Maryland
- HealthPartners Institute dba International Diabetes Center — Minneapolis, Minnesota
- SKY Integrative Medical Center/SKYCRNG — Ridgeland, Mississippi
- Boeson Research MSO — Missoula, Montana
- Palm Research Center Tenaya — Las Vegas, Nevada
- Palm Research Center Sunset — Las Vegas, Nevada
- Albany Medical College, Division of Community Endocrinology — Albany, New York
- Research Foundation of SUNY - University of Buffalo — Buffalo, New York
- NYC Research — New York, New York
- SUNY Upstate Medical University — Syracuse, New York
- Lucas Research, Inc. — Morehead City, North Carolina
- Care Access - Lima — Lima, Ohio
- Alliance for Multispecialty Research, LLC — Norman, Oklahoma
- Suburban Research Associates — West Chester, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Type 1 Diabetes
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- Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families — Jacksonville, Florida
- Diabetes Inspired Culinary Education (DICE): Culinary Medicine Intervention for At-Risk Youth With Type 1 Diabetes — Cleveland, Ohio
- GO TEAM: Glucose Optimization Through Technology Assisted Management — Cleveland, Ohio
- REAL-Fam Feasibility Study for Youth Diabetes Management — Chapel Hill, North Carolina
- Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes — New York, New York
Explore by condition: All Type 1 Diabetes clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.