๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-28

A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening) (NCT06948422)

A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants With Hypertension and Obesity or Overweight: Randomized, Double-Blind, Placebo-Controlled Trials (ATTAIN-HYPERTENSION)

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The GZPL master protocol will support 2 independent studies, J2A-MC-GZL1 (GZL1) and J2A-MC-GZL2 (GZL2). The purpose of this study is to create a framework to evaluate the safety and efficacy of orforglipron for the treatment of hypertension in participants with obesity or overweight.

Who can join: Review the eligibility criteria below.

Location: Elite Clinical Studies, LLC โ€” Phoenix, Arizona

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (100 Sites)

Showing the first 25 of 100 sites.

  • Elite Clinical Studies, LLC โ€” Phoenix, Arizona
  • Valley Clinical Trials, Inc. โ€” Covina, California
  • Valley Clinical Trials, Inc. โ€” Northridge, California
  • Chase Medical Research, LLC โ€” Waterbury, Connecticut
  • Excel Medical Clinical Trials โ€” Boca Raton, Florida
  • Care Access - Brandon โ€” Brandon, Florida
  • Northeast Research Institute - Downtown Office โ€” Jacksonville, Florida
  • Care Access - St. Petersburg โ€” St. Petersburg, Florida
  • East-West Medical Research Institute โ€” Honolulu, Hawaii
  • Sinai Hospital Of Baltimore โ€” Baltimore, Maryland
  • Ascension Saint Agnes Heart Care โ€” Baltimore, Maryland
  • Lucida Clinical Trials โ€” New Bedford, Massachusetts
  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division โ€” Troy, Michigan
  • StudyMetrix Research โ€” City of Saint Peters, Missouri
  • Excel Clinical Research, LLC โ€” Las Vegas, Nevada
  • Palm Research Center Sunset โ€” Las Vegas, Nevada
  • Rochester Clinical Research, LLC โ€” Rochester, New York
  • Remington-Davis, Inc โ€” Columbus, Ohio
  • PriMED Clinical Research โ€” Dayton, Ohio
  • Advanced Research Institute - Tigard โ€” Tigard, Oregon
  • Care Access - Mauldin โ€” Mauldin, South Carolina
  • Dallas Heart and Vascular Consultants, PA โ€” Duncanville, Texas
  • Texas Institute of Cardiology, PA โ€” McKinney, Texas
  • North Hills Family Medicine/North Hills Medical Research โ€” North Richland Hills, Texas
  • Advanced Research Institute โ€” Ogden, Utah

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Hypertension clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—