🏛️ Verified NIH Record • Updated 2026-05-28
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1 (NCT06948435)
A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants With Hypertension and Obesity or Overweight: Randomized, Double-Blind, Placebo-Controlled Trials (ATTAIN-HYPERTENSION)
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Eli Lilly and Company
🩺 Plain-English Summary (8th-Grade Level)
GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.
Who can join: Review the eligibility criteria below.
Location: Elite Clinical Studies, LLC — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (99 Sites)
Showing the first 25 of 99 sites.
- Elite Clinical Studies, LLC — Phoenix, Arizona
- Valley Clinical Trials, Inc. — Covina, California
- Valley Clinical Trials, Inc. — Northridge, California
- Chase Medical Research, LLC — Waterbury, Connecticut
- Excel Medical Clinical Trials — Boca Raton, Florida
- Care Access - Brandon — Brandon, Florida
- Northeast Research Institute - Downtown Office — Jacksonville, Florida
- Peace River Cardiovascular Center — Port Charlotte, Florida
- East-West Medical Research Institute — Honolulu, Hawaii
- Ascension Saint Agnes Heart Care — Baltimore, Maryland
- Lucida Clinical Trials — New Bedford, Massachusetts
- Arcturus Healthcare , PLC, Troy Internal Medicine Research Division — Troy, Michigan
- StudyMetrix Research — City of Saint Peters, Missouri
- Excel Clinical Research, LLC — Las Vegas, Nevada
- Palm Research Center Sunset — Las Vegas, Nevada
- Rochester Clinical Research, LLC — Rochester, New York
- Remington-Davis, Inc — Columbus, Ohio
- PriMED Clinical Research — Dayton, Ohio
- Advanced Research Institute - Tigard — Tigard, Oregon
- Care Access - Mauldin — Mauldin, South Carolina
- Dallas Heart and Vascular Consultants, PA — Duncanville, Texas
- Texas Institute of Cardiology, PA — McKinney, Texas
- North Hills Family Medicine/North Hills Medical Research — North Richland Hills, Texas
- Advanced Research Institute — Ogden, Utah
- Carient Heart & Vascular - Manassas — Manassas, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hypertension
- Implementing a Home Blood Pressure Monitoring Program in Primary Care — New York, New York
- SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN — Birmingham, Alabama
- Stress and Blood Pressure Management for Caregivers — Columbus, Ohio
- Caveolin-1 and Vascular Dysfunction — Boston, Massachusetts
- The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension — Birmingham, Alabama
- Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County — Irvine, California
Explore by condition: All Hypertension clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.