Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome (NCT06953466)
A Single Center, Open Label, Expanded Access Study of QRX003 Lotion in Subjects With Netherton Syndrome
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial (via an expanded access Treatment Protocol) is to learn if QRX003 (an investigational drug) applied topically to the skin (including up to the entire body \[except the scalp\]) works to treat the genetic disease Netherton syndrome. It will also learn about the safety of QRX003. The main questions the trial aims to answer are: 1. Does QRX003 impact the clinical presentation of NS in adults and minors by improving the clinical symptoms (diseased skin area, itch, and discomfort; based on clinical scoring, subject self-assessment, and other criteria)? 2. What medical problems do participants have when taking QRX003? 3. What percent of subjects will require rescue therapy? Participants will: Take drug QRX003 twice daily (applied topically to all affected areas of the body excluding the scalp) for 3 months, visit the clinic once every 4-6 weeks for checkups and tests, and to keep a dosing diary that records the times they applied the drug.
Who can join: Review the eligibility criteria below.
Location: Northwestern Memorial Hospital — Chicago, Illinois
Age range: 14 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Northwestern Memorial Hospital — Chicago, Illinois
📞 Contact the Study Coordinator
Phone: (858) 571-1800
Email: clinicalresearch@therapeuticsinc.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Netherton Syndrome
- Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome — San Diego, California
- Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome — San Diego, California
- Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome — Fremont, California
- A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725 — Palo Alto, California
Explore by condition: All Netherton Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.