A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes (NCT06972472)
A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Tablet Once Daily Compared With Placebo in Participants With Obesity or Overweight With and Without Type 2 Diabetes
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to see how orforglipron, compared with placebo, helps improve glycemic control in participants with obesity or with overweight and type 2 diabetes. This trial is part of the master protocol study J2A-MC-GZPO (NCT06993792). Participation in the study will last about 18 months.
Who can join: Review the eligibility criteria below.
Location: Clinical Research Institute of Arizona (CRI) - Sun City West — Sun City West, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (80 Sites)
Showing the first 25 of 80 sites.
- Clinical Research Institute of Arizona (CRI) - Sun City West — Sun City West, Arizona
- Novak Clinical Research - Tucson - North La Cholla Boulevard — Tucson, Arizona
- Norcal Endocrinology & Internal Medicine — San Ramon, California
- Southern California Clinical Research — Santa Ana, California
- Care Access - Thousand Oaks — Thousand Oaks, California
- Accel Research Sites - DeLand Clinical Research Unit — DeLand, Florida
- Innovation Medical Research Center - Fort Lauderdale — Fort Lauderdale, Florida
- Indago Research & Health Center, Inc — Hialeah, Florida
- Encore Medical Research — Hollywood, Florida
- West Orange Endocrinology P.A. — Ocoee, Florida
- Care Access - Tampa — Tampa, Florida
- Conquest Research — Winter Park, Florida
- Accel Research Sites - NeuroStudies Clinical Research Unit — Decatur, Georgia
- Care Access - Decatur — Decatur, Georgia
- Javara - Privia Medical Group Georgia - Savannah — Savannah, Georgia
- North Georgia Clinical Research — Woodstock, Georgia
- Solaris Clinical Research — Meridian, Idaho
- Care Access - New Iberia — New Iberia, Louisiana
- Endocrine and Metabolic Consultants — Rockville, Maryland
- Javara - Privia Medical Group - Silver Spring — Silver Spring, Maryland
- Great Lakes Research Group, Inc. — Bay City, Michigan
- Boeson Research MSO — Missoula, Montana
- Javara - Nevada Health Centers - Carson City — Carson City, Nevada
- The Machuca Foundation — Las Vegas, Nevada
- University of North Carolina Medical Center — Chapel Hill, North Carolina
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.