🏛️ Verified NIH Record • Updated 2026-08-27

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) (NCT06979596)

A Multicenter, Open-label, Phase 2 Basket Study of MK-5684 in Participants With Selected Solid Tumors (OMAHA-015)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Merck Sharp & Dohme LLC

🩺 Plain-English Summary (8th-Grade Level)

Researchers want to learn if MK-5684 (the study medicine) can treat breast cancer, ovarian cancer, and endometrial cancer. MK-5684, the study medicine, is designed to treat cancer by blocking the body from making steroid hormones. Researchers will compare MK-5684 to the standard treatments for each cancer type in this study. The goal of this study is to learn if people who receive MK-5684 live longer without the cancer growing or spreading compared to people who receive a standard treatment.

Who can join: Review the eligibility criteria below.

Location: Alaska Womens Cancer Care ( Site 0037) — Anchorage, Alaska

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (59 Sites)

Showing the first 25 of 59 sites.

  • Alaska Womens Cancer Care ( Site 0037) — Anchorage, Alaska
  • Mount Sinai Cancer Center ( Site 0009) — Miami Beach, Florida
  • TRIALS 365 ( Site 0022) — Shreveport, Louisiana
  • Mary Lanning Healthcare ( Site 0019) — Hastings, Nebraska
  • John Theurer Cancer Center at Hackensack University Medical Center ( Site 0021) — Hackensack, New Jersey
  • Rockefeller Outpatient Pavilion ( Site 0002) — New York, New York
  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0008) — Columbus, Ohio
  • Baylor College of Medicine Medical Center ( Site 0004) — Houston, Texas
  • Harris Health System ( Site 0040) — Houston, Texas
  • Mays Cancer Center ( Site 0039) — San Antonio, Texas
  • Hospital Aleman ( Site 0301) — Ciudad Autonoma de Buenos Aires, Buenos Aires
  • Centro Medico Dr. Doreski - Fundación Respirar ( Site 0302) — Buenos Aires, Buenos Aires F.D.
  • Instituto Alexander Fleming ( Site 0303) — Buenos Aires, Buenos Aires F.D.
  • Hospital Santa Rita de Cassia ( Site 3104) — Vitória, Espírito Santo
  • Obras Sociais Irma Dulce ( Site 3112) — Salvador, Estado de Bahia
  • Hospital Felicio Rocho ( Site 3105) — Belo Horizonte, Minas Gerais
  • Hospital de Cancer de Pernambuco ( Site 3103) — Recife, Pernambuco
  • Liga Norte Riograndense Contra o Cancer ( Site 3108) — Natal, Rio Grande do Norte
  • Instituto Nacional de Câncer - INCA ( Site 3107) — Rio de Janeiro,
  • Princess Margaret Cancer Centre ( Site 0202) — Toronto, Ontario
  • Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0200) — Montreal, Quebec
  • Jewish General Hospital ( Site 0201) — Montreal, Quebec
  • Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer ( Site 0205) — Sherbrooke, Quebec
  • FALP ( Site 3300) — Santiago, Region M. de Santiago
  • Pontificia Universidad Catolica de Chile ( Site 3307) — Santiago, Region M. de Santiago

📞 Contact the Study Coordinator

Phone: (888) 577-8839

Email: Trialsites@msd.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗