🏛️ Verified NIH Record • Updated 2026-05-26

A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma (NCT06988488)

A Phase 1b/2a, Multicenter, Open-label Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma

🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: Celgene

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the preliminary safety and determine the RP2D of mezigdomide in combination with elranatamab in participants with relapsed and refractory multiple myeloma (RRMM).

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham — Birmingham, Alabama

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (22 Sites)

  • University of Alabama at Birmingham — Birmingham, Alabama
  • Yale New Haven Hospital-Smilow Cancer Center — New Haven, Connecticut
  • Hackensack University Medical Center — Hackensack, New Jersey
  • University of Texas MD Anderson Cancer Center — Houston, Texas
  • Arthur J E Child Comprehensive Cancer Centre — Calgary, Alberta
  • Local Institution - 0026 — Vancouver, British Columbia
  • QEII Health Sciences Centre - Victoria General Site — Halifax, Nova Scotia
  • Princess Margaret Cancer Centre — Toronto, Ontario
  • Local Institution - 0030 — Suzhou, Jiangsu
  • Local Institution - 0031 — Shanghai, Shanghai Municipality
  • Universitaetsklinikum Carl Gustav Carus Dresden — Dresden,
  • Universitaetsklinikum Hamburg-Eppendorf — Hamburg,
  • Universitaetsklinikum Heidelberg — Heidelberg,
  • Evangelismos General Hospital of Athens — Athens, Attikí
  • Alexandra General Hospital of Athens — Athens, Attikí
  • St. Olavs Hospital — Trondheim, Sør-Trøndelag
  • Sykehusapoteket Ull — Oslo,
  • Hospital Universitario Marqués de Valdecilla — Santander, Cantabria
  • Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca — Salamanca,
  • University College London Hospital — London, England
  • Royal Marsden Hospital (Sutton) — London, Sutton
  • The Christie NHS Foundation Trust — Manchester,

📞 Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗