πŸ›οΈ Verified NIH Record β€’ Updated 2026-08-03

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol (NCT07028749)

Phase 2b Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study of MAR001 in Patients With Elevated Triglycerides and Remnant Cholesterol (TYDAL-TIMI 78)

🟒 Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: Marea Therapeutics

🩺 Plain-English Summary (8th-Grade Level)

The primary objective of the study is to evaluate the effect of MAR001 compared to placebo on levels of TG in adults with elevated TG and RC.

Who can join: Review the eligibility criteria below.

Location: Marea Site 328 β€” Anniston, Alabama

Age range: 18 Years to 75 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (54 Sites)

Showing the first 25 of 54 sites.

  • Marea Site 328 β€” Anniston, Alabama
  • Marea Site 329 β€” Mobile, Alabama
  • Marea Site 313 β€” Little Rock, Arkansas
  • Marea Site 306 β€” Hamden, Connecticut
  • Marea Site 302 β€” Boca Raton, Florida
  • Marea Site 307 β€” Port Saint Lucie, Florida
  • Marea Site 310 β€” Columbus, Georgia
  • Marea Site 319 β€” Peachtree Corners, Georgia
  • Marea Site 317 β€” Park Ridge, Illinois
  • Marea Site 325 β€” Springfield, Illinois
  • Marea Site 301 β€” Louisville, Kentucky
  • Marea Site 316 β€” Baltimore, Maryland
  • Marea Site 330 β€” Kansas City, Missouri
  • Marea Site 305 β€” St Louis, Missouri
  • Marea Site 304 β€” Great Neck, New York
  • Marea Site 318 β€” New Windsor, New York
  • Marea Site 303 β€” Greensboro, North Carolina
  • Marea Site 315 β€” Winston-Salem, North Carolina
  • Marea Site 314 β€” Greenville, South Carolina
  • Marea Site 320 β€” Little River, South Carolina
  • Marea Site 326 β€” Memphis, Tennessee
  • Marea Site 322 β€” Amarillo, Texas
  • Marea Site 308 β€” McKinney, Texas
  • Marea Site 312 β€” San Antonio, Texas
  • Marea Site 321 β€” Manassas, Virginia

πŸ“ž Contact the Study Coordinator

Phone: (415) 766-3610

Email: TYDAL_info@mareatx.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—