The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments (NCT07050264)
🩺 Plain-English Summary (8th-Grade Level)
Burn survivors have difficulty thermoregulating due to reduced skin blood flow and sweating responses at the grafted sites. It has been previously shown that this impaired heat dissipation results in burn survivors experiencing higher core temperatures for a given exercise/environmental exposure compared to non-burned individuals. This also holds true with the use of simulated burn injury. When an absorbent material is applied to the skin over a desired amount of body surface area, it replicates a burn injury of the same size (i.e., simulated burn injury). A question that remains unknown is if this impaired thermoregulation in burn survivors would affect post-exercise core temperature recovery, i.e., do burn survivors recover slower than non-burned individuals upon stopping exercise. To that end, the primary objective of this project is to determine the rate at which body temperature and other markers of thermoregulation recover after a bout of exercise in the heat and if this response is different in the same individual with and without simulated burn injury.
Who can join: Review the eligibility criteria below.
Location: Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital Dallas — Dallas, Texas
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
- Simulated burn injury via application of absorbent and impermeable material over 60% of the body (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital Dallas — Dallas, Texas
📞 Contact the Study Coordinator
Phone: (214) 345-4737
Email: erin.harper2@utsouthwestern.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Burn Injury
- STAT: Standard Therapy Plus Active Therapy — Phoenix, Arizona
- Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial — Pittsburgh, Pennsylvania
- Mitochondrial Energy Metabolism in Burns — Little Rock, Arkansas
- Skin Wetting in Burn Survivors — Dallas, Texas
Explore by condition: All Burn Injury clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.