Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD (NCT07051707)
A Multicenter, Randomized, Study to Evaluate Safety and Efficacy After Treatment With the dNerva Lung Denervation System in Subjects With Chronic Obstructive Pulmonary Disease (COPD) (AIRFLOW-4)
🩺 Plain-English Summary (8th-Grade Level)
The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System in the treatment of COPD.
Who can join: Review the eligibility criteria below.
Location: University of Alabama-Birmingham Hospital - UAB Lung Health Center — Birmingham, Alabama
Age range: 40 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- University of Alabama-Birmingham Hospital - UAB Lung Health Center — Birmingham, Alabama
- Mayo Clinic Jacksonville — Jacksonville, Florida
- Henry Ford Hospital - Lung and Pulmonary Care — Detroit, Michigan
- Wake Forest School of Medicine — Salem, North Carolina
- Ohio State University Medical Center - Ohio State Lung Center — Columbus, Ohio
- Penn Highlands - Lung Innovations/Clinical Research Associates — DuBois, Pennsylvania
- Temple University - Temple Lung Center — Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center - UMPC Comprehensive Lung Center — Pittsburgh, Pennsylvania
- Virginia Commonwealth University Health System — Richmond, Virginia
- Medical College of Wisconsin — Milwaukee, Wisconsin
📞 Contact the Study Coordinator
Phone: (763) 450-2819
Email: jcarline@nuvaira.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.