🏛️ Verified NIH Record • Updated 2026-08-19
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes (NCT07061574)
🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: City of Hope Medical Center
🩺 Plain-English Summary (8th-Grade Level)
This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from randomization in persons aged 9 to \<21 with recent-onset stage 3 T1D.
Who can join: Review the eligibility criteria below.
Location: UCSF — San Francisco, California
Age range: 9 Years to 20 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (11 Sites)
- UCSF — San Francisco, California
- Barbara Davis Center for Diabetes University of Colorado Anschutz — Aurora, Colorado
- Yale University — New Haven, Connecticut
- University of Florida — Gainesville, Florida
- University of Miami — Miami, Florida
- Indiana University — Indianapolis, Indiana
- University of Minnesota — Minneapolis, Minnesota
- University of Buffalo — Buffalo, New York
- University of Pittsburgh — Pittsburgh, Pennsylvania
- Baylor College of Medicine — Houston, Texas
- Seattle Children's Hospital — Seattle, Washington
📞 Contact the Study Coordinator
Phone: (813) 975-8690
Email: rhenderson@jaeb.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Type 1 Diabetes
- A 12-week Pilot Nutrition Intervention for Children With New Diagnosis of Stage 3 Type 1 Diabetes (T1D) — Hershey, Pennsylvania
- Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families — Jacksonville, Florida
- Diabetes Inspired Culinary Education (DICE): Culinary Medicine Intervention for At-Risk Youth With Type 1 Diabetes — Cleveland, Ohio
- GO TEAM: Glucose Optimization Through Technology Assisted Management — Cleveland, Ohio
- REAL-Fam Feasibility Study for Youth Diabetes Management — Chapel Hill, North Carolina
- Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes — New York, New York
Explore by condition: All Type 1 Diabetes clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.