๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-12

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors (NCT07066657)

An Open-Label, Multi-Center, Dose Escalation, Confirmation, and Expansion Phase I Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of MRG007 (ARR-217) in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: ArriVent BioPharma, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is an open-label, multi-center, phase I study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of MRG007 (ARR-217) in patients with unresectable locally advanced or metastatic solid tumors.

Who can join: Review the eligibility criteria below.

Location: ULCA โ€” Los Angeles, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (21 Sites)

  • ULCA โ€” Los Angeles, California
  • UCSF โ€” San Francisco, California
  • University of Colorado โ€” Aurora, Colorado
  • Sarah Cannon Research Institute โ€” Denver, Colorado
  • Sarah Cannon Research Institute โ€” Sarasota, Florida
  • Sarah Cannon Research Institute โ€” Nashville, Tennessee
  • MD Anderson Cancer Center โ€” Houston, Texas
  • NEXT Dallas โ€” Irving, Texas
  • NEXT Virginia โ€” Fairfax, Virginia
  • Fred Hutchinson Cancer Center โ€” Seattle, Washington
  • Peking University Cancer Hospital โ€” Beijing, Beijing Municipality
  • Beijing Gobroad Hospital โ€” Beijing, Beijing Municipality
  • Chongqing Daping Hospital โ€” Chongqing, Chongqing Municipality
  • Sir Run Run Shaw Hospital, Zhejiang University School of Medicine โ€” Zhejiang, Hangzhou
  • Harbin Medical University Cancer Hospital โ€” Heilongjiang, Harbin
  • Henan Cancer Hospital โ€” Zhengzhou, Henan
  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology โ€” Wuhan, Hubei
  • Hunan Cancer Hospital โ€” Changsha, Hunan
  • Cancer Hospital of Shandong First Medical University โ€” Shandong, Jinan
  • Renji Hospital Shanghai Jiaotong University School of Medicine โ€” Shanghai, Shanghai Municipality
  • Zhongshan Hospital Fudan University โ€” Shanghai, Shanghai Municipality

๐Ÿ“ž Contact the Study Coordinator

Phone: (888) 622-2827

Email: ClinicalTrials.gov@ArriVent.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—