๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-07-16

Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait (NCT07083531)

Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait

๐ŸŸข Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: UConn Health

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a cross-sectional, clinical research study comparing postmenopausal women of African Descent (AD) with different hemoglobin genotypes: normal and sickle cell trait (SCT). This research study has two purposes. The first purpose is to determine whether having SCT is a risk factor for the development of bone thinning in older women. The second purpose is to investigate whether women with SCT have reduced muscle function and increased frailty compared to women without SCT. The investigators estimate enrolling 50 female volunteers who are at least 50 years old and have not had a menstrual period for at least 12 consecutive months. Volunteers need not know whether they have SCT as this will be evaluated as part of the study.

Who can join: Review the eligibility criteria below.

Location: UConn Health โ€” Farmington, Connecticut

Age range: 50 Years

๐Ÿงช Interventions in This Study

  • Healthy volunteers without SCT (OTHER)
  • Healthy volunteers with SCT (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • UConn Health โ€” Farmington, Connecticut

๐Ÿ“ž Contact the Study Coordinator

Phone: (860) 679-4656

Email: zgreen@uchc.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—