๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-20

A Study of Herbal Supplements in Cancer Survivors With Constipation (NCT07091084)

Herbal Formula Ma-Zi-Ren-Wan (MZRW) on Bowel Movement Function and Gut Microbiome Among Cancer Survivors With Constipation: A Double-blinded Randomized Controlled Trial (RELIEVE)

๐ŸŸข Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to find out whether MZRW is an effective treatment for constipation in cancer survivors. The researchers will compare MZRW with placebo, a pill that looks like MZRW and is given in the same way, but contains no medication. The researchers will also study the effect MZRW has on the gut microbiome. The gut microbiome is a diverse community of microorganisms living in the digestive system, essential for digestion and immune function.

Who can join: Review the eligibility criteria below.

Location: Memorial Sloan Kettering Basking Ridge (All Protocol Activities) โ€” Basking Ridge, New Jersey

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (7 Sites)

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities) โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth (All Protocol Activities) โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen (All Protocol Activities) โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities) โ€” Commack, New York
  • Memorial Sloan Kettering Westchester (All Protocol Activities) โ€” Harrison, New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) โ€” New York, New York
  • Memorial Sloan Kettering Nassau (All Protocol Activities) โ€” Rockville Centre, New York

๐Ÿ“ž Contact the Study Coordinator

Phone: (646) 608-8552

Email: maoj@mskcc.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Constipation clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—