πŸ›οΈ Verified NIH Record β€’ Updated 2026-07-29

Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma (NCT07096778)

A Phase II, Open-Label, Multicenter Study of Inobrodib in Combination With Pomalidomide and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

🟒 Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: CellCentric Ltd.

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to learn more about the anti-cancer activity of inobrodib, when given in combination with pomalidomide and dexamethasone, in patients with multiple myeloma that has come back following treatment and which no longer responds to available therapies. The study treatment will not be compared to any other treatment and patients will know what treatment they are receiving. This study will also further explore the side effects of inobrodib in combination with these other medicines.

Who can join: Review the eligibility criteria below.

Location: Mayo Clinic Arizona β€” Phoenix, Arizona

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (30 Sites)

Showing the first 25 of 30 sites.

  • Mayo Clinic Arizona β€” Phoenix, Arizona
  • University of California, San Francisco β€” San Francisco, California
  • Mayo Clinic Florida β€” Jacksonville, Florida
  • H Lee Moffitt Cancer Center & Research Institute β€” Tampa, Florida
  • Winship Cancer Institute β€” Atlanta, Georgia
  • University of Chicago Medical Center β€” Chicago, Illinois
  • American Oncology Partners, PA β€” Bethesda, Maryland
  • Dana-Farber Cancer Institute β€” Boston, Massachusetts
  • University of Michigan β€” Ann Arbor, Michigan
  • Mayo Clinic β€” Rochester, Minnesota
  • Washington University School of Medicine β€” St Louis, Missouri
  • University of Nebraska Medical Center β€” Omaha, Nebraska
  • John Theurer Cancer Center at Hackensack University Medical Center β€” Hackensack, New Jersey
  • Rutgers Cancer Institute of New Jersey β€” New Brunswick, New Jersey
  • Levine Cancer Institute β€” Charlotte, North Carolina
  • Wake Forest University Health Sciences β€” Winston-Salem, North Carolina
  • Cleveland Clinic β€” Cleveland, Ohio
  • University of Pennsylvania, Abramson Cancer Center β€” Philadelphia, Pennsylvania
  • Fred Hutchinson Cancer Center β€” Seattle, Washington
  • Froedtert Hospital & the Medical College of Wisconsin β€” Milwaukee, Wisconsin
  • The Christie NHS Foundation Trust β€” Withington, Greater Manchester
  • Royal Marsden NHS Foundation Trust β€” Sutton, London
  • University Hospital of Wales β€” Cardiff, Wales
  • The Clatterbridge Cancer Centre NHS Foundation Trust β€” Bebington, Wirral
  • Western General Hospital β€” Edinburgh,

πŸ“ž Contact the Study Coordinator

Phone: +44 1799 531130

Email: DOMMINO-1@cellcentric.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—