Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging (NCT07099053)
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging (BLSA)
🩺 Plain-English Summary (8th-Grade Level)
Background: Some people experience cognitive decline as they age. That is, they lose memory, problem-solving, and other mental abilities. Amyloids are groups of proteins that develop in the brain and increase in number as people age. Researchers want to use imaging scans to track amyloids in people s brains over time. Their goal is to find out if any changes are related to cognitive decline or other medical issues. Objective: To learn how amyloids may affect brain structure and function as people age. Eligibility: People aged 55 years and older who are enrolled in the Baltimore Longitudinal Study of Aging. Design: Participants will have imaging scans and other tests every 1 to 4 years, depending on their age. Those 80 and older will be scanned yearly. These scans will be done during regular BLSA visits. The scans will be positron emission tomography and computed tomography (PET CT). Participants will be given fluid through a tube inserted into a vein in their arm. The fluid is a tracer that will cause the amyloids to light up in the images. Then they will lie on a bed with their head inside a PET CT scanner. They will lie still for about 30 minutes. Participants will have tests to assess their memory and other mental skills. They will answer questions about their mood and daily life. These tests will take about 40 minutes to complete; they may be done in person or by phone. Participants will give a contact number for someone who can answer questions about the participant s daily routine. These questions may be answered in person or by phone. Participants will be in this study for 5 years.
Who can join: Review the eligibility criteria below.
Location: National Institute of Aging, Clinical Research Unit — Baltimore, Maryland
Age range: 55 Years to 110 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- National Institute of Aging, Clinical Research Unit — Baltimore, Maryland
📞 Contact the Study Coordinator
Phone: (410) 558-8610
Email: wendy.elkins@nih.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aging
- A Pilot Study on Reverse Aging (The REVERSE Study) — Cincinnati, Ohio
- Feasibility of Home-based tES for Older Adults at Risk of Falling — Roslindale, Massachusetts
- Heat, Microvascular Function and Aging — Milwaukee, Wisconsin
- Protein Quantity and Quality in Older Subjects — Hamilton, Ontario
- Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse — Salt Lake City, Utah
- Effect of a Daily Supplement on Plasma PAI-1 Levels — Los Angeles, California
Explore by condition: All Aging clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.