Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies (NCT07102641)
PACESS: Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
🩺 Plain-English Summary (8th-Grade Level)
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks. Multimodal non-opioid pain medications, including acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) are the preferred first-line therapies. There is no standard practice, however, on best dosing schedules (ie staggered or different time v. simultaneous or same time). This protocol describes a randomized clinical trial aimed to determine whether staggered dosing of acetaminophen and NSAIDs in superior to simultaneous dosing in controlling post-cesarean pain.
Who can join: Review the eligibility criteria below.
Location: Thomas Jefferson University Hospital — Philadelphia, Pennsylvania
Age range: 16 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Thomas Jefferson University Hospital — Philadelphia, Pennsylvania
📞 Contact the Study Coordinator
Phone: (434) 294-8416
Email: whitney.bender@jefferson.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cesarean Delivery
- IC-CS Risk: Patient Outcomes — Ann Arbor, Michigan
- Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery — New York, New York
- BUprenorphine Versus Morphine for Postcesarean Analgesia (BUMP) — New York, New York
- Duration of Urinary Catheterization Following Cesarean Deliveries Under Neuraxial Anesthesia — Vancouver, British Columbia
- Suzetrigine for Opioid-Free Recovery After Cesarean Delivery — Austin, Texas
Explore by condition: All Cesarean Delivery clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.