🏛️ Verified NIH Record • Updated 2026-07-28
A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis (NCT07105488)
A Phase 2, Parallel-arm, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy and Safety of BFB759 in Patients With Atopic Dermatitis (COMPASS 2-AD)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Bluefin Biomedicine, Inc.
🩺 Plain-English Summary (8th-Grade Level)
This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.
Who can join: Review the eligibility criteria below.
Location: Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute — Phoenix, Arizona
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (88 Sites)
Showing the first 25 of 88 sites.
- Mountain West Derm - Blackhart PLLC dba Skin Cancer and Dermatology Institute — Phoenix, Arizona
- Skin Cancer and Dermatology Institute — Phoenix, Arizona
- T. Joseph Raoof Md, Inc — Encino, California
- Marvel Clinical Research — Huntington Beach, California
- Antelope Valley Clinical Trials — Lancaster, California
- Probity Medical Research — Los Angeles, California
- NorCal Clinical Research — Rocklin, California
- Focus Clinical Research, LLC -S — West Hills, California
- Skin Care Research — Boca Raton, Florida
- Florida Academic Dermatology Center Res and Edu, LLC — Coral Gables, Florida
- Center for Skin Science and Innovation — Fort Lauderdale, Florida
- Gsi Clinical Research — Margate, Florida
- Ziaderm Research LLC — North Miami Beach, Florida
- Lenus Research & Medical Group, LLC — Sweetwater, Florida
- Clinical Trials Management - S — Tampa, Florida
- Conquest Research LLC — Winter Park, Florida
- Skin Cancer and Dermatology Institute — Douglasville, Georgia
- Southeast Research Specialists, LLC — Douglasville, Georgia
- The Indiana Clinical Trials Center — Plainfield, Indiana
- Clinical Trials Management - S — Covington, Louisiana
- Clinical Trials Management, LLC — Metairie, Louisiana
- MetroBoston Clinical Partners — Brighton, Massachusetts
- Oakland Hills Dermatology — Auburn Hills, Michigan
- MI Skin Innovations — Northville, Michigan
- Medisearch, LLC — Saint Joseph, Missouri
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atopic Dermatitis (AD)
- Effectiveness of Psychodermatologic Educational Modules on Atopic Dermatitis Patient Outcomes — Edmonton, Alberta
- Moisturization and Skin Hydration Study — Vancouver, British Columbia
- Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis — Fargo, North Dakota
- The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis — Pittsburgh, Pennsylvania
- Effect of an Emollient Cream Containing a Milk Bioactive Peptide on Clinical Signs, Pruritus and Bacterial Colonization of Mild Atopic Dermatitis Skin Lesions in Pediatric Population — Aguascalientes, Aguascalientes
Explore by condition: All Atopic Dermatitis (AD) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.