Optimal Ventilation for Cardiac Arrest (NCT07114510)
OPTImal Ventilation to Improve Pediatric Cardiac Arrest Outcomes (OPTI-VENT)
🩺 Plain-English Summary (8th-Grade Level)
Pediatric cardiac arrest is a life-threatening problem affecting \>15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors. The objective of this study is to evaluate the effectiveness of the OPTI-VENT bundle to improve survival to discharge with favorable neurological outcome (Pediatric Cerebral Performance Category Score 1-2 or no change from baseline) among children receiving at least 1 minute of CPR.
Who can join: Review the eligibility criteria below.
Location: CHOC — Orange, California
Age range: 37 Weeks to 18 Years
🧪 Interventions in This Study
- OPTI-VENT Bundle (OTHER)
- Transition (OTHER)
- None - control (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (20 Sites)
- CHOC — Orange, California
- Lucile Packard Children's Hospital Stanford — Palo Alto, California
- Children's Hospital Colorado — Denver, Colorado
- Nemours Children's Health — Wilmington, Delaware
- Children's Healthcare of Atlanta — Atlanta, Georgia
- Riley Children's Health — Indianapolis, Indiana
- Stead Family Children's Hospital — Iowa City, Iowa
- Boston Children's Hospital — Boston, Massachusetts
- Washington University in St. Louis — St Louis, Missouri
- Cohen Children's Medical Center — New Hyde Park, New York
- UNC Children's Hospital — Chapel Hill, North Carolina
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio
- Nationwide Children's Hospital — Columbus, Ohio
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania
- Dell Children's Medical Center — Austin, Texas
- Medical City Children's Hospital — Dallas, Texas
- UT Southwestern Medical Center — Dallas, Texas
- Children's Hospital of Richmond at VCU — Richmond, Virginia
- Seattle Children's — Seattle, Washington
- Children's Wisconsin — Milwaukee, Wisconsin
📞 Contact the Study Coordinator
Phone: (215) 590-1859
Email: grahamk1@chop.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiac Arrest (CA)
- Pulse Detection in Cardiac Arrest Patients Using a Doppler Ultrasound Patch on the Carotid Artery — Manhasset, New York
- PRECISION-CPR: PRecision-Controlled Ventilation in CPR — Chicago, Illinois
- Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm — Québec, Quebec
- The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial) — Pittsburgh, Pennsylvania
- The VENTOR Clinical Study — Stony Brook, New York
- Identification of Brain Injury Using Portable MRI — New Haven, Connecticut
Explore by condition: All Cardiac Arrest (CA) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.