Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers (NCT07116876)
An Open-Label Trial to Assess the Clinical Effectiveness of Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers
🩺 Plain-English Summary (8th-Grade Level)
This study will evaluate Matrion™ (LifeNet Health, Inc., Virginia Beach, VA), a placental membrane product, as a treatment for diabetic foot ulcers compared to conventional wound care. Matrion is derived from donated human birth tissue and includes both the amniotic and chorionic layers, along with the trophoblast layer. It is minimally processed using a proprietary decellularization method and terminally sterilized to ensure the membrane is acellular and sterile, making it suitable for surgical applications.
Who can join: Review the eligibility criteria below.
Location: Compass Medical Research Center — Tucson, Arizona
Age range: 21 Years to 80 Years
🧪 Interventions in This Study
- Graft Application (OTHER)
- Wound Dressing Material (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (18 Sites)
- Compass Medical Research Center — Tucson, Arizona
- Bay Area Foot Care — Castro Valley, California
- Limb Preservaion Platform, Inc. — Fresno, California
- Center for Clinical Research, Inc — San Francisco, California
- Bay Area Foot Care — San Francisco, California
- ILD Research Center — Vista, California
- Humanity Clinical Research, Corp — Aventura, Florida
- South Florida Podiatry — Deerfield Beach, Florida
- Dinamo Research & Diagnostic Center, LLC — Hialeah, Florida
- Doctors Research Network, Inc. — Miami, Florida
- Independent Clinical Research — Decatur, Illinois
- Independent Clinical Research, LLC — Springfield, Illinois
- US Foot and Ankle Specialists — Raleigh, North Carolina
- Foot and Ankle Institute of the Carolinas — Rocky Mount, North Carolina
- Olympus Clinical Research — Katy, Texas
- Element Research Group — San Antonio, Texas
- Olympus-Alcanza — Sugar Land, Texas
- Foot and Ankle Specialists of the Mid-Atlantic — Salem, Virginia
📞 Contact the Study Coordinator
Phone: (520) 526-2325
Email: Heather.Kimbriel@gmail.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Diabetic Foot Ulcer (DFU)
- Real-World Effectiveness of Amniotic Membrane Allografts Versus Standard Wound Care in DFU, VLU, and PU — Colorado Springs, Colorado
- Remote Temperature and Visual Monitoring To Help Manage Diabetic Foot Ulcers — North Port, Florida
- HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU — Novi, Michigan
- Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing — Chicago, Illinois
- Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers — Hollywood, Florida
- CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations — Oxnard, California
Explore by condition: All Diabetic Foot Ulcer (DFU) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.