๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-30

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers (NCT07118176)

PET Imaging Study of 68Ga-FAPI-46 Biodistribution in Cancer Patients

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿฉบ Clinical Procedure Protocol Sponsor: Jonsson Comprehensive Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase I trial is evaluating a new imaging tracer (68Ga-FAPi-46) with positron emission tomography (PET)/computed tomography (CT) to determine where and to which degree the tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues (the biodistribution) in patients with solid tumors or hematologic (blood) cancers. PET is an established imaging technique that utilizes small amounts of radioactivity attached to very minimal amounts of tracer, in the case of this research, 68Ga-FAPi-46. Because some cancers take up 68Ga-FAPi-46, it can be seen with PET. CT utilizes x-rays that traverse the body from the outside. CT images provide an exact outline of organs and potential inflammatory tissue where it occurs in a patient's body. Combining a PET scan with a CT scan can help make the image easier to interpret. PET/CT scans are hybrid scanners that combine both modalities into a single scan during the same examination.

Who can join: Review the eligibility criteria below.

Location: UCLA / Jonsson Comprehensive Cancer Center โ€” Los Angeles, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Computed Tomography (PROCEDURE)
  • Fludeoxyglucose F-18 (OTHER)
  • Gallium Ga 68 FAPi-46 (RADIATION)
  • Positron Emission Tomography (PROCEDURE)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • UCLA / Jonsson Comprehensive Cancer Center โ€” Los Angeles, California

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—