๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-26

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension (NCT07142356)

A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multicenter Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Retension Pharmaceuticals. Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The goal of this clinical trial is to learn if the drug RT-001 works to reduce high blood pressure (hypertension) in adults. It will also learn about the safety of RTN-001. The main questions it aims to answer are: Does RTN-001 lower blood pressure in patients who have uncontrolled hypertension? What medical problems do participants have when taking RTN-001? Researchers will compare RTN-001 to a placebo (a look-alike substance that contains no drug) to see if RTN-001 works to treat uncontrolled hypertension. Participants will: Take RTN-001 or a placebo every day for 12 weeks Visit the clinic about once every 2 weeks for checkups and tests Keep a diary of their symptoms and all medications that they take including RTN-001

Who can join: Review the eligibility criteria below.

Location: Retension Clinical Site โ€” Tucson, Arizona

Age range: 18 Years to 70 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (22 Sites)

  • Retension Clinical Site โ€” Tucson, Arizona
  • Retension Clinical Site โ€” San Jose, California
  • Retension Clinical Site โ€” West Hills, California
  • Retension Clinical Site โ€” Waterbury, Connecticut
  • Retension Clinical Site โ€” Orlando, Florida
  • Retension Clinical Site โ€” Port Orange, Florida
  • Retension Clinical Site โ€” Tampa, Florida
  • Retension Clinical Site โ€” Lawrenceville, Georgia
  • Retension Clinical Site โ€” Peachtree Corners, Georgia
  • Retension Clincial Site โ€” Boston, Massachusetts
  • Retension Clinical Site โ€” Las Vegas, Nevada
  • Retension Clinical Site โ€” Las Vegas, Nevada
  • Retension Clinical Site โ€” Asheboro, North Carolina
  • Retension Clinical Site โ€” Charlotte, North Carolina
  • Retension Clinical Site โ€” Monroe, North Carolina
  • Retension Clinical Site โ€” Cincinnati, Ohio
  • Retension Clinical Site โ€” Charleston, South Carolina
  • Retension Clinical Site โ€” Bellaire, Texas
  • Retension Clinical Site โ€” Dallas, Texas
  • Retension Clincal Site โ€” Plano, Texas
  • Retension Clinical Site โ€” San Antonio, Texas
  • Retension Clinical Site โ€” Vienna, Virginia

๐Ÿ“ž Contact the Study Coordinator

Phone: (703) 624-2024

Email: info@retensionpharmaceuticals.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Uncontrolled Hypertension

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—