Who is eligible for clinical trial NCT07155226?

Participants must meet protocol criteria for Acute Lymphoblastic Leukaemia. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT07155226 provide travel or cost reimbursement?

The protocol indicates compensation for participation. Confirm stipend details with the site coordinator.

🏛️ Verified NIH Record • Updated 2026-07-17

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression (NCT07155226)

A Modular Phase I/II, Open-label, Multi-Centre Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to understand the safety, tolerability, efficacy, pharmacokinetic (PK), pharmacodynamic (PD), and preliminary efficacy of orally administered AZD3632 in participants with advanced haematologic malignancies with KMT2Ar, NPM1m, or other genotypes associated with homeobox (HOX) overexpression.

Who can join: Review the eligibility criteria below.

Location: Research Site — Decatur, Illinois

Age range: 16 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (30 Sites)

Showing the first 25 of 30 sites.

Research Site — Decatur, Illinois
Research Site — New York, New York
Research Site — Chapel Hill, North Carolina
Research Site — Durham, North Carolina
Research Site — Portland, Oregon
Research Site — Houston, Texas
Research Site — Fitzroy,
Research Site — Perth,
Research Site — Toronto, Ontario
Research Site — Montreal, Quebec
Research Site — Copenhagen,
Research Site — Dresden,
Research Site — Frankfurt A. Main,
Research Site — Halle,
Research Site — Heidelberg,
Research Site — München,
Research Site — Ulm,
Research Site — Bologna,
Research Site — Ravenna,
Research Site — Bunkyō City,
Research Site — Kashiwa,
Research Site — Okayama,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Seoul,

📞 Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Acute Lymphoblastic Leukaemia

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia — Buenos Aires,

Explore by condition: All Acute Lymphoblastic Leukaemia clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗