🏛️ Verified NIH Record • Updated 2026-03-31

Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris (NCT07205107)

Satisfaction, Adherence, Effectiveness, and Safety of Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Treatment in Patients With Acne Vulgaris: A Canadian Prospective Phase IV Study (CHARM)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Bausch Health Americas, Inc.

🩺 Plain-English Summary (8th-Grade Level)

The goal of this observational study is to learn about the effects of a treatment that contains clindamycin phosphate, adapalene, and benzoyl peroxide in people with acne. The main questions the study aims to answer are: * How satisfied are people with this treatment? * How well do people follow the treatment plan? * How effective and safe is the treatment? * How does the treatment affect quality of life? * How do people use other skin care products, such as cleansers, moisturizers, and sunscreen, while using this treatment? About 200 people aged 12 and older with acne across Canada will use the treatment as part of their regular care and answer questions about their experience over 20 weeks.

Who can join: Review the eligibility criteria below.

Location: CHARM Site 007 — Calgary, Alberta

Age range: 12 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (19 Sites)

  • CHARM Site 007 — Calgary, Alberta
  • CHARM Site 001 — Edmonton, Alberta
  • CHARM Site 017 — Surrey, British Columbia
  • CHARM Site 012 — Vancouver, British Columbia
  • CHARM Site 003 — Winnipeg, Manitoba
  • CHARM Site 021 — Hamilton, Ontario
  • CHARM Site 010 — Markham, Ontario
  • CHARM Site 013 — Newmarket, Ontario
  • CHARM Site 022 — North York, Ontario
  • CHARM Site 015 — Ottawa, Ontario
  • CHARM Site 011 — Richmond Hill, Ontario
  • CHARM Site 016 — Toronto, Ontario
  • CHARM Site 005 — Toronto, Ontario
  • CHARM Site 014 — Toronto, Ontario
  • CHARM Site 002 — Toronto, Ontario
  • CHARM Site 019 — Windsor, Ontario
  • CHARM Site 008 — Montreal, Quebec
  • CHARM Site 006 — Pointe-Claire, Quebec
  • CHARM Site 018 — Québec, Quebec

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Acne Vulgaris clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗