DIAPHRAGM STRENGTH AND LUNG VOLUMES (NCT07206459)
Diaphragm Strength and Lung Volumes
🩺 Plain-English Summary (8th-Grade Level)
Diaphragm dysfunction (loss of diaphragm strength) is common in the intensive care unit (ICU) patients using ventilators. The diaphragm is the main muscle of respiration and its dysfunction can prolong mechanical ventilation and increase mortality risk. The ventilator settings determine how much air and pressure the patient gets every breath and how much air is left on the lungs after they breathe out. The amount of air left on the lungs influence diaphragm strength measurements which can affect clinical decisions, such as weaning patients off ventilators. This research aims to explore the relationship between the amount of air left in the lungs and diaphragm strength to create a method of correcting measurements of diaphragm strength according to how much air the patients have in the lungs after they breath out. The investigators will test healthy individuals to understand this relationship, then verify if it holds true for ventilated patients by comparing results from both groups.
Who can join: Review the eligibility criteria below.
Location: St. Michael's Hospital — Toronto, Ontario
Age range: 18 Years
🧪 Interventions in This Study
- Healthy Patients (OTHER)
- Critically Care Patients (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- St. Michael's Hospital — Toronto, Ontario
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mechanical Ventilation
- Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts — Columbus, Ohio
- Ketamine Sedation in the ICU (KANINE) RCT — Hamilton, Ontario
- Optimizing Pain Treatment in Children On Mechanical Ventilation — Little Rock, Arkansas
- Analgesia-First Sedation in Trauma Patients — Long Beach, California
- Prognostic Estimates Among ICU Clinicians — Chicago, Illinois
Explore by condition: All Mechanical Ventilation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.