A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (NCT07213674)
A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
🩺 Plain-English Summary (8th-Grade Level)
The primary objective of this study is to compare overall survival (OS) in participants receiving xaluritamig plus abiraterone against investigator's choice (docetaxel, cabazitaxel, or abiraterone).
Who can join: Review the eligibility criteria below.
Location: City of Hope Cancer Center Phoenix — Goodyear, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (151 Sites)
Showing the first 25 of 151 sites.
- City of Hope Cancer Center Phoenix — Goodyear, Arizona
- University of Arizona Cancer Center — Tucson, Arizona
- City of Hope National Medical Center — Duarte, California
- City of Hope Orange County Lennar Foundation Cancer Center — Duarte, California
- Providence Saint Jude Medical Center — Fullerton, California
- University of California Irvine — Orange, California
- University of California San Francisco — San Francisco, California
- Providence Saint Johns Health Center — Santa Monica, California
- Rocky Mountain Cancer Centers — Denver, Colorado
- Hartford HealthCare Cancer Institute at Hartford Hospital — Hartford, Connecticut
- Medical Oncology Hematology Consultants Helen F Graham Cancer Center — Newark, Delaware
- Moffitt Cancer Center — Tampa, Florida
- City of Hope Atlanta — Newnan, Georgia
- University of Illinois Chicago — Chicago, Illinois
- Midwestern Regional Medical Center dba City of Hope Chicago — Zion, Illinois
- University of Kansas Medical Center — Westwood, Kansas
- University of Louisville Health - James Graham Brown Cancer Center — Louisville, Kentucky
- Norton Cancer Institute — Louisville, Kentucky
- University of Maryland Greenebaum Cancer Center — Baltimore, Maryland
- Johns Hopkins Hospital Sidney Kimmell Comprehensive Cancer Center — Baltimore, Maryland
- Barbara Ann Karmanos Cancer Institute — Lansing, Michigan
- Minnesota Oncology Hematology PA — Minneapolis, Minnesota
- University of Minnesota Medical Center Fairview — Minneapolis, Minnesota
- Hematology Oncology Association of Central New York — East Syracuse, New York
- Memorial Sloan Kettering Cancer Center — New York, New York
📞 Contact the Study Coordinator
Phone: (866) 572-6436
Email: medinfo@amgen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Metastatic Castration-resistant Prostate Cancer
- A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer — San Francisco, California
- Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment — Tucson, Arizona
- ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC — Sacramento, California
- FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) — Duarte, California
- A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer — Duarte, California
- FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer — San Francisco, California
Explore by condition: All Metastatic Castration-resistant Prostate Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.