Quantification of Progenitor Cell Circulation Following Vascular Resistance Exercise Using Delfi Tourniquet System (NCT07213726)
Quantification of Peripheral Hematopoietic Progenitor Cell Circulation Following Repeated Acute, Vascular Restriction Resistance Exercise Using the Delfi Tourniquet System
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this observational study is to examine how slowing down blood flow to the legs- a practice called blood flow restriction (BFR)- during exercise by applying compression to the legs affects the way stem cells are released into the blood stream. This will be determined by drawing 6 cubic centimeters (ccs) of blood immediately post-exercise after the Delfi Personalized Tourniquet System (PTS) has been removed. 6 ccs of blood will also be taken prior to exercise and at the 20-, 40-, and 60-minute marks after exercise. The main question of this study is: • Will the levels of stem cells extracted before and after exercise be the same if blood flow is restricted during exercise? In this study, participants will undergo the following: * 6 ccs of blood extracted from the forearm prior to exercise to establish a baseline * 3 exercises- seated leg extension, semi-reclined leg press, and seated hamstring curl- consisting of 4 sets of 30-15-15-15 repetitions per exercise; resistance will be set to 30% of one-rep maximum (1-RM) * Additional 6 cc blood draws will be performed immediately post-exercise and after 20, 40, and 60 minutes have elapsed
Who can join: Review the eligibility criteria below.
Location: Andrews Institute for Orthopaedics & Sports Medicine — Gulf Breeze, Florida
Age range: 18 Years to 45 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Andrews Institute for Orthopaedics & Sports Medicine — Gulf Breeze, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Blood Flow Restriction (BFR) Training Effects clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.