๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-11

Small Trial of Alendronate Impact on the Reservoir of HIV (NCT07216794)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This clinical trial is designed to test the effects of alendronate (ALN) on people living with HIV who are already receiving antiretroviral therapy (ART). Participants are randomly assigned in a 2:1 ratio to either receive alendronate or a placebo, and neither the participants nor the researchers know who is receiving the actual treatment. The goal is to see if alendronate can reduce the size and activity of the HIV-1 reservoir in these individuals.

Who can join: Review the eligibility criteria below.

Location: University of California, San Francisco HIV/AIDS (Site ID: 801) โ€” San Francisco, California

Age range: 18 Years to 65 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • University of California, San Francisco HIV/AIDS (Site ID: 801) โ€” San Francisco, California
  • University of Colorado Hospital (Site ID: 6101) โ€” Aurora, Colorado
  • Chapel Hill (Site ID: 3201) โ€” Chapel Hill, North Carolina
  • Ohio State University (Site ID: 2301) โ€” Columbus, Ohio
  • University of Pittsburgh (Site ID: 1001) โ€” Pittsburgh, Pennsylvania

๐Ÿ“ž Contact the Study Coordinator

Phone: (919) 904-9668

Email: nataliasorsar@gwu.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All HIV clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—