๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-01

Trial of Neoadjuvant THP vs TCHP for HER2-Amplified/Positive Breast Cancer (NCT07220135)

A Randomized Trial of Neoadjuvant THP vs TCHP for HER2-amplified/Positive Breast Cancer (NeoTHERa)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: University of Kansas Medical Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a randomized phase II study to evaluate the pathological complete response (pCR) rate with two neoadjuvant regimens (Docetaxel+Carboplatin+Herceptin/Perjeta and Docetaxel+Herceptin/Perjeta) in HER2 amplified/positive early breast cancer.

Who can join: Review the eligibility criteria below.

Location: The University of Kansas Cancer Center (KUCC) โ€” Fairway, Kansas

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (8 Sites)

  • The University of Kansas Cancer Center (KUCC) โ€” Fairway, Kansas
  • The University of Kansas Cancer Center - Westwood โ€” Kansas City, Kansas
  • KUCC - Indian Creek โ€” Overland Park, Kansas
  • KUCC - Overland Park โ€” Overland Park, Kansas
  • KUCC - Briarcliff โ€” Westwood, Kansas
  • KUCC - Olathe โ€” Westwood, Kansas
  • The University of Kansas Cancer Center - North โ€” Kansas City, Missouri
  • KUCC - Lee's Summit โ€” Lee's Summit, Missouri

๐Ÿ“ž Contact the Study Coordinator

Phone: (913) 588-3671

Email: kucc_navigation@kumc.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Breast Cancer clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—