🏛️ Verified NIH Record • Updated 2026-06-30
A Study of TLC590 for Postsurgical Pain Following Bunionectomy (NCT07222748)
A Phase 3, Randomized, Double-blind, Comparator- and Placebo-controlled Study to Evaluate the Safety and Efficacy of TLC590 for Postsurgical Pain Management Following Bunionectomy
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: TLC Biopharmaceuticals, Inc.
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase 3, randomized, double-blind, comparator- and placebo-controlled study to evaluate analgesic efficacy and safety of TLC590 via local infiltration in adult subjects following bunionectomy.
Who can join: Review the eligibility criteria below.
Location: Clinical Pharmacology of Miami — Miami, Florida
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Clinical Pharmacology of Miami — Miami, Florida
- First Surgical Hospital — Bellaire, Texas
- Memorial Hermann Village — Houston, Texas
- Endeavor Clinical Trials — San Antonio, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Postoperative Pain
- No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair — Fountain Valley, California
- Perioperative Lidocaine and Ketamine in Abdominal Surgery — Weston, Florida
- Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks — Tucson, Arizona
- Personalizing Perioperative Analgesia in Children — Pittsburgh, Pennsylvania
- Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation — New York, New York
Explore by condition: All Postoperative Pain clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.